Adipose tissue in cardiovascular disease: From basic science to clinical translation

MD Polkinghorne, HW West… - Annual Review of …, 2024 - annualreviews.org
… See credit lines of images or other third-party material in this … by the presence of stem cell
surface markers [including … by oxidative stress), leading to permanent cell cycle arrest and …

From patient-specific induced pluripotent stem cells to clinical translation in long QT syndrome Type 2

PJ Schwartz, M Gnecchi, F Dagradi… - European heart …, 2019 - academic.oup.com
… Thus, more specific and patient-tailored therapies are still needed. The introduction of induced
pluripotent stem cell (… 5 allow testing new therapeutic approaches on patient-specific cells. …

[HTML][HTML] Perspectives for clinical translation of adipose stromal/stem cells

M Patrikoski, B Mannerström, S Miettinen - Stem Cells International, 2019 - hindawi.com
… to clinical trials, although investigating human cells in animal models is always challenging.
Further, we discuss safety aspects related to clinical translations… Thus, guidance in support of …

Artificially engineered cubic iron oxide nanoparticle as a high-performance magnetic particle imaging tracer for stem cell tracking

Q Wang, X Ma, H Liao, Z Liang, F Li, J Tian, D Ling - ACS nano, 2020 - ACS Publications
Stem cell therapies are increasingly recognized as the future … stem cells remains a major
concern for clinical translation, … blur the PSF in the scan direction, leading to a decrement of …

Towards clinical translation of FLASH radiotherapy

MC Vozenin, J Bourhis, M Durante - Nature Reviews Clinical Oncology, 2022 - nature.com
… become feasible thanks to improvements in image-guided radiotherapy, additionally sparing
non-… effects on differentiated, progenitor and stem cells, followed by indirect stimulation of …

Chasing the paradigm: clinical translation of 25 years of tissue engineering

T Hoffman, A Khademhosseini… - Tissue Engineering Part …, 2019 - liebertpub.com
… to the development and clinical translation of tissue engineering-inspired therapies, leading
to an … Examples include cell sources of induced pluripotent stem cells (A) [Photo courtesy of …

3D Bioprinting of cardiac tissue and cardiac stem cell therapy

M Alonzo, S AnilKumar, B Roman, N Tasnim… - Translational …, 2019 - Elsevier
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in most … imaged
cardiac structures like ventricular chambers or valve leaflets. However, ultrasound imaging

Mesoporous bioactive glasses in cancer diagnosis and therapy: stimuli‐responsive, toxicity, immunogenicity, and clinical translation

E Sharifi, A Bigham, S Yousefiasl, M Trovato… - Advanced …, 2022 - Wiley Online Library
… malignant cells and the presence of cancer stem cells. … MBGs with diagnostic imaging and/or
therapeutic purposes that … cells (ie, in most cases both tumor and normal cells), leading to …

Regenerating the field of cardiovascular cell therapy

KR Chien, J Frisén, R Fritsche-Danielson… - Nature …, 2019 - nature.com
stem cell therapy, cardiac regeneration may have been the most compelling case for
translating fundamental advances in stem cell … considering clinical translation of the approach. …

Actively targeted nanomedicines for precision cancer therapy: Concept, construction, challenges and clinical translation

W Gu, F Meng, R Haag, Z Zhong - Journal of controlled release, 2021 - Elsevier
… in the AML cells of majority patients but not on pluripotent stem cells. Calicheamicin is …
clinical benefits and increased mortality rate of GO therapy over standard chemotherapy, leading